DNA Compaction And Its Association With Diseases

Scientists at TLL have identified a specific type of protein which is responsible for the compaction of DNA. This compaction affects the way information flows from genomic DNA and has an impact on evolution, life and certain diseases. Irregular compaction of DNA plays a role in disease and is commonly associated with cancer. In a normal cell, DNA is compacted in well-defined areas, whereas in a cancer cell, the degree and structure of DNA compaction is abnormal.